MassVentures Opens START Grant Applications to Help Startups Translate Research into Companies and Jobs

MassVentures Opens START Grant Applications to Help Startups Translate Research into Companies and Jobs 

Funding supports Massachusetts SBIR Phase II companies moving federally funded innovations from lab to market 

BOSTON — Today, the Healey-Driscoll Administration and MassVentures announced that applications are now open for the next round of its SBIR Targeted Technologies (START) Grant Program, which provides non-dilutive funding to Massachusetts companies that have received federal SBIR (Small Business Innovation Research) or STTR (Small Business Technology Transfer) Phase II awards. The program helps startups translate advanced research into commercial products, new businesses, and high-quality jobs across Massachusetts. 

START grants provide $100,000 to $500,000 to eligible companies to support critical commercialization activities, including market validation, business development, and intellectual property strategy, that are not typically covered by federal research funding. In addition to capital, participating companies receive business guidance to accelerate go-to-market progress across sectors such as advanced materials, quantum computing, AI, cleantech, and biotechnology. 

“Supporting entrepreneurs at the earliest stages is critical to building a strong innovation economy,” said Massachusetts Economic Development Secretary Eric Paley, Chair of the MassVentures Board of Directors. “START grants provide founders in high-impact sectors with the resources they need to grow, hire, and succeed in Massachusetts—while advancing solutions to some of the world’s most pressing challenges.” 

MassVentures launched the START program in 2012, and this year marks the program’s 15th year supporting high-impact Massachusetts innovators. 

In FY25, with increased funding through the Mass Leads Act, MassVentures expanded the number of annual START awards from 17 to 26. Over its 15-year history, START has awarded $41.7 million to 141 companies that have employed more than 3,300 and leveraged more than $5 billion in private capital. The businesses are located in more than 40 communities throughout Massachusetts.  

“START grants address one of the most persistent challenges facing deep tech founders: proving commercial viability before traditional capital becomes available," said MassVentures President and CEO Charlie Hipwood. "This program helps Massachusetts businesses validate their technologies, build teams, and hit the milestones needed to attract follow-on investment—keeping our state's most promising innovations here in the Commonwealth.” 

Applications opened February 1 and are due February 23. Massachusetts-based companies which have won a SBIR/STTR Phase 2 in the past 5 years are encouraged to apply. For more information, join MassVentures for an information session on February 3 at 8:00 a.m. or visit https://www.mass-ventures.com/start-program-info.